Correlation between serum ferritin level and severity of dengue fever in a tertiary care center: an observational study

Background: Serum ferritin is an acute phase protein and elevated levels of have been associated with the pathogenesis many inflammatory infectious viral diseases. Dengue a mosquito-borne tropical infection that caused by dengue virus. TNF? interleukin 1?, another proinflammatory cytokine, transcriptionally induce H-chain ferritin. Therefore, serum can be used as prognostic marker for severity.Methods: This case control study conducted between July 2017 to December 2018.Results: On 3rd day fever, median values in dengue, fever without warning signs, severe were 513.5 ng/ml, 1002 ng/ml 2352.4 respectively. 7th 474 900 2949 1247 on 3 has sensitivity 96.4% specificity 91% prediction severity. Area under curve was 0.963 (95% confidence limit: 0.934-0.991). 1050 7 98.2 % 93% 0.977 0.957-0.998).Conclusions: Elevation significantly seen those dengue. Day